desperate Play adjectiveFeeling or showing a hopeless sense that a situation is so bad as to be impossible to deal with. SYNONYMS anguishedat one's wits' endat the end of one's tetherbeside oneselfdefeatistdemoralizeddesolatedespairingdevastateddiscourageddishearteneddistraughtdistresseddolorousdowncastforlornfraughthopelessin despairmiserableout of one's mindovercomepessimisticresignedsuicidalwretched