despair

noun

The complete loss or absence of hope.

verb

Lose or be without hope.

SYNONYMS

anguishdefeatismdejectiondepressiondesperationdespondencydisconsolatenessdiscouragementdisheartenmentdistressforlornnessgloomhopelessnessmelancholiamelancholymiserypainpessimismresignednessunhappinesswretchedness