depressions Play nounFeelings of severe despondency and dejection. SYNONYMS clinical depressiondejectiondesolationdespairdespondencydisconsolatenessdisconsolationdiscouragementdispiritednessdolefulnessdolourdownheartednessdysthymiaendogenous depressiongloomgloominessheavy-heartednesshopelessnesslow spiritsmelancholiamelancholymiserymoodinessmoperymorosenessone's black dogpessimismpostnatal depressionreactive depressionsadnesssorrowtearfulnessthe blahsthe bluesthe doldrumsthe dumpsthe megrimsthe mopesthe slough of despondunhappinessupsetwoe