noun

physical weakness, especially as a result of illness.

most of the cases presented with general debility, muscle weakness, and weight loss

frailty,weakness,feebleness,enfeeblement,enervation,devitalization,lack of energy,lack of vitality,lassitude,exhaustion,weariness,tiredness,overtiredness,fatigue,prostration,incapacity,impairment,indisposition,infirmity,illness,sickness,sickliness,decrepitude,malaise,weediness,asthenia