manipulate

To move, arrange, operate, or control by the hands or another body part or by mechanical means, especially in a skillful manner: synonym: handle.

To influence or manage shrewdly or deviously.

To tamper with or falsify for personal gain.

To handle and move in an examination or for therapeutic purposes.

To handle, or act on with the hands, as in artistic or mechanical operations; hence, in general, to subject to certain mechanical operations or to some method of handling, arranging, combining, etc.