adjective

feeling or expressing distress or irritation.

the baby was crying with a fretful whimper

distressed,upset,miserable,unsettled,uneasy,ill at ease,uncomfortable,agitated,distraught,overwrought,wrought up,worked up,tense,stressed,restive,fidgety,irritable,cross,crabbed,fractious,peevish,petulant,out of sorts,bad-tempered,ill-natured,edgy,irascible,grumpy,crotchety,touchy,captious,testy,tetchy,querulous,complaining,grumbling,whining,cranky,het up,uptight,twitchy,rattled,crabby,overstrung,unquiet