noun

serious attention or consideration applied to doing something correctly or to avoid damage or risk.

he planned his departure with great care

caution,carefulness,wariness,awareness,heedfulness,heed,attention,attentiveness,alertness,watchfulness,vigilance,circumspection,prudence,guardedness,observance,discretion,judiciousness,forethought,thought,regard,mindfulness,conscientiousness,painstakingness,pains,effort,meticulousness,punctiliousness,fastidiousness,accuracy,precision

verb

feel concern or interest; attach importance to something.

they don’t care about human life

be concerned,worry (oneself),trouble oneself,bother,mind,concern oneself with,be interested in,interest oneself in,trouble oneself with,have regard for,burden oneself with,give a damn,give a hoot,give a rap,give a hang,give a tinker’s curse/damn,give a monkey’s,lose sleep over,get worked up