despite

dɪˈspʌɪt

preposition

without being affected by; in spite of.

he remains a great leader despite age and infirmity

in spite of,notwithstanding,regardless of,in defiance of,without being affected by,in the face of,for all,even with,undeterred by

noun

contemptuous treatment or behaviour; outrage.

the despite done by him to the holy relics